Effects of Electronic (e)-Cigarette Vapor on Staphylococcal Virulence: Are E-Cigarettes Safer than Conventional Cigarettes?
نویسندگان
چکیده
In recent years, electronic (e)‐cigarettes have dramatically increased in popularity as an alternative to conventional cigarettes. Little is known about the effects of e‐cigarette vapor (EV) on bacteria that colonize the nasopharynx, including methicillin‐resistant Staphylococcus aureus (MRSA). As most cases of pneumonia can be traced to bacteria in a patient's nasopharynx, increased virulence in potential pathogens could have direct consequences clinically for these patients. And because bacterial colonizers are spread between humans, increased virulence in one subject has implications for the community. There is accumulating evidence that exposure to cigarette smoke (CS) increases the pathogenicity of MRSA, as well as its dampening effects on the host immune system. EV exposure has also been demonstrated to increase MRSA virulence both in vitro and in a murine model of pneumonia. In this chapter, we will compare the virulence changes reported in MRSA exposed to CS vs. those exposed to EV, as well as proposed mechanisms and therapeutic targets.
منابع مشابه
Electronic cigarette vapor alters the lateral structure but not tensiometric properties of calf lung surfactant
BACKGROUND Despite their growing popularity, the potential respiratory toxicity of electronic cigarettes (e-cigarettes) remains largely unknown. One potential aspect of e-cigarette toxicity is the effect of e-cigarette vapor on lung surfactant function. Lung surfactant is a mixture of lipids and proteins that lines the alveolar region. The surfactant layer reduces the surface tension of the alv...
متن کاملPerceptions about e-cigarette safety may lead to e-smoking during pregnancy.
Electronic cigarettes (e-cigarettes) are nicotine-delivery devices that are increasingly used, especially by young people. Because e-cigarettes lack many of the substances found in regular tobacco, they are often perceived as a safer smoking alternative, especially in high-risk situations such as pregnancy. However, studies suggest that it is exposure to nicotine that is most detrimental to pre...
متن کاملE-Cigarettes: Use, Effects on Smoking, Risks, and Policy Implications.
Since e-cigarettes appeared in the mid-2000s, some practitioners, researchers, and policy makers have embraced them as a safer alternative to conventional cigarettes and an effective way to stop smoking. While e-cigarettes deliver lower levels of carcinogens than do conventional cigarettes, they still expose users to high levels of ultrafine particles and other toxins that may substantially inc...
متن کاملElectronic Cigarette (E-Cigarette) Using: Toxicological Aspects
INTRODUCTION Electronic nicotine delivery systems (ENDS), which can be as also called “personal vaporizer”, “vape pen”, “e-waterpipe”, or “e-cigarette”, have become increasingly popular in recent years (1). The supporters of ENDS argue that the users are exposed to lesser chemicals, and these systems help quit smoking, and thus, ENDSs are safer than cigarettes (2). E-cigarette is a product that...
متن کاملCarbonyl Compounds Generated from Electronic Cigarettes
Electronic cigarettes (e-cigarettes) are advertised as being safer than tobacco cigarettes products as the chemical compounds inhaled from e-cigarettes are believed to be fewer and less toxic than those from tobacco cigarettes. Therefore, continuous careful monitoring and risk management of e-cigarettes should be implemented, with the aim of protecting and promoting public health worldwide. Mor...
متن کامل